Examination of natural gums as matrices for sustained release of theophylline.
نویسندگان
چکیده
منابع مشابه
Hydrophilic Natural Polymers for Sustained-controlled Release of Calcium Hydroxide
Calcium Hydroxide (CH) is commonly employed as intracanal medicament in endodontics. In order to maximize its therapeutic effects, it is essential to develop new approaches for preparing the controlled drug release systems which, in turn, facilities the dissociation of CH into calcium and hydroxyl ions. This work studies the sustained-controlled release of calcium ions and the effect of pH chan...
متن کاملHydrophilic Natural Polymers for Sustained-controlled Release of Calcium Hydroxide
Calcium Hydroxide (CH) is commonly employed as intracanal medicament in endodontics. In order to maximize its therapeutic effects, it is essential to develop new approaches for preparing the controlled drug release systems which, in turn, facilities the dissociation of CH into calcium and hydroxyl ions. This work studies the sustained-controlled release of calcium ions and the effect of pH chan...
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Objective(s) The aim of this study was to formulate and evaluate microencapsulated controlled release preparations of theophylline using ethylcellulose as the retardant material with high entrapment efficiency. Materials and Methods Microspheres were prepared by water-in-oil-in-oil (W/O1/O2) emulsion-solvent diffusion (ESD). A mixed solvent system consisting of acetonitrile and dichloromet...
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The objective of this study was to design and evaluate oral sustained drug delivery system for Metoprolol succinate using natural hydrophilic gums such as karaya gum and xanthan gum as a release modifier. Nine batches were prepared by using karaya gum (KG) and xanthan gum (XG) in concentration of 15%, 20% and 25% alone and in combination of 2:8. Matrix tablets were prepared by wet granulation m...
متن کاملRelease of Theophylline from Sustained Release Cylindrical Dosage Forms
The holt-melt extrusion technique has proven to be an advantageous method for preparation of solid dosage forms. The aim of this work was to evaluate the release profiles of sustained release cylinders produced by hot-melt extrusion. The cylinders were composed of inner and outer part, both containing theophylline [1]. Cylinders were 0.5cm or 1cm long. The two parts were extruded separately, cu...
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ژورنال
عنوان ژورنال: Chemical and Pharmaceutical Bulletin
سال: 1984
ISSN: 0009-2363,1347-5223
DOI: 10.1248/cpb.32.782